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<?xml version="1.0" encoding="UTF-8"?>

<channelml xmlns="http://morphml.org/channelml/schema"
    xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
    xmlns:meta="http://morphml.org/metadata/schema"
    xsi:schemaLocation="http://morphml.org/channelml/schema  http://www.neuroml.org/NeuroMLValidator/NeuroMLFiles/Schemata/v1.8.1/Level2/ChannelML_v1.8.1.xsd"
    units="SI Units"
>


    
<meta:notes>A channel from Maex, R and De Schutter, E. Synchronization of Golgi and Granule Cell Firing in a
    Detailed Network Model of the Cerebellar Granule Cell Layer
</meta:notes>
    
    
<channel_type name="Gran_KCa_98">
        
        
<status value="stable">
            
<meta:issue>This ChannelML file is intended ONLY to replicate the original GENESIS functionality. A new Granule cell model is being developed based on
                D'Angelo et al 2001 and Berends, Maex and De Schutter 2005, and the ChannelML files will be updated
</meta:issue>
            
<meta:contributor>
                
<meta:name>Padraig Gleeson</meta:name>
            
</meta:contributor>
        
</status>
    
        
<meta:notes>Calcium concentration dependent K+ channel</meta:notes>
    
        
<meta:authorList>
            
<meta:modelAuthor>
                
<meta:name>Maex, R.</meta:name>
            
</meta:modelAuthor>
            
<meta:modelAuthor>
                
<meta:name>De Schutter, E.</meta:name>
            
</meta:modelAuthor>
            
<meta:modelTranslator>
                
<meta:name>Padraig Gleeson</meta:name>
                
<meta:institution>UCL</meta:institution>    
                
<meta:email>p.gleeson - at - ucl.ac.uk</meta:email>
            
</meta:modelTranslator>
        
</meta:authorList>
        
        
<meta:publication>
          
<meta:fullTitle>Maex, R and De Schutter, E.
           Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the
           cerebellar Granule Cell Layer. J Neurophysiol, Nov 1998; 80: 2521 - 2537
</meta:fullTitle>
          
<meta:pubmedRef>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=9819260&amp;dopt=Abstract</meta:pubmedRef>
        
</meta:publication>

        
<meta:neuronDBref>
            
<meta:modelName>K+ channels</meta:modelName>
            
<meta:uri>http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3</meta:uri>
        
</meta:neuronDBref>

        
<current_voltage_relation cond_law="ohmic" ion="k" default_gmax="0.179811" default_erev="-0.09">
            
            
<conc_dependence name="Calcium" ion="ca" charge="2" variable_name="ca_conc" min_conc="7.55e-7" max_conc="0.050"/>
            
            
<q10_settings q10_factor="3" experimental_temp="17.350264793"/>
            
<offset value="0.010"/>
            
            
<gate name="m" instances="1">
                
<closed_state id="m0"/>
                
<open_state id="m"/>
                    
                
<transition name="alpha" from="m0" to="m" expr_form="generic" expr="2500/(1 + ( (1.5e-3 *(exp (-85*v))) / ca_conc))" />
                
<transition name="beta" from="m" to="m0" expr_form="generic" expr="1500/(1 + (ca_conc / (1.5e-4 * (exp (-77*v)))))" />
                    
            
</gate>
        
</current_voltage_relation>        
      
        
        
    
</channel_type>
</channelml>