Transforming XML file: NeuroMLFiles/Examples/ChannelMLSyns/STDPSynapse.xml using XSL file: NeuroMLFiles/Schemata/v1.8.1/Level3/NeuroML_Level3_v1.8.1_HTML.xsl

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Converting the file: STDPSynapse.xml

General notes
Notes present in ChannelML file
ChannelML file describing a plastic synaptic mechanism

Unit system of ChannelML file
This can be either SI Units or Physiological Units (milliseconds, centimeters, millivolts, etc.)
Physiological Units

Synapse: STDPSynapse

NameSTDPSynapse
Status
Status of element in file
Stable
Contributor: Padraig Gleeson
Description
As described in ChannelML file
Example of a synaptic mechanism incorporating Spike Timing Dependent Plasticity

Synaptic Mechanism Model: Spike Timing Dependent Plasticity

The model underlying the synaptic mechanism

Maximum conductance
The peak conductance which the synapse will reach
2E-9 mS
Rise time
Characteristic time (tau) over which the double exponential synaptic conductance rises
1 ms
Decay time
Characteristic time (tau) over which the double exponential synaptic conductance decays
1 ms
Reversal potential
The effective reversal potential for the ion flow through the synapse when the conductance is non zero
0 mV

Plasticity element of synaptic model

How the magnitude of the response changes due to spike times

Time constant LTP
The time constant for potentiation of synaptic strength when a postsynaptic spike follows a pre
20 ms
Weight change LTP
The change in weight (as a fraction of maximum conductance above) when a postsynaptic spike instantaneously follows a pre. Note the magnitude of this change will decay with time constant given above.
0.1
Time constant LTD
The time constant for depression of synaptic strength when a presynaptic spike follows a post
20 ms
Weight change LTD
The change in weight (as a fraction of maximum conductance above) when a presynaptic spike instantaneously follows a post. Note the magnitude of this change will decay with time constant given above.
0.105
Maximum synaptic weight
The maximum weight to which the synapse can increase, as a multiple of maximum conductance above
2
Post synaptic threshold
The membrane potential of the post synaptic cell which should be considered a spike
-50 mV

Time to transform file: 0.113 secs