Transforming XML file: NeuroMLFiles/Examples/ChannelML/IntFireMechanism.xml using XSL file: NeuroMLFiles/Schemata/v1.8.1/Level3/NeuroML_Level3_v1.8.1_HTML.xsl

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Converting the file: IntFireMechanism.xml

General notes
Notes present in ChannelML file
A cell mechanism for creating a simple integrate and fire cell

Unit system of ChannelML file
This can be either SI Units or Physiological Units (milliseconds, centimeters, millivolts, etc.)
Physiological Units

Channel: IandF

As described in the ChannelML file
A simple integrate and fire mechanism, which is based on the implementation in NEURON of the COBA IandF cell as described in Brette et al (2007)
Translators of the model to NeuroML:
   Padraig Gleeson  (UCL)  p.gleeson - at -
Reference in ModelDB Networks of spiking neurons: a review of tools and strategies (Brette et al. 2007)
Current voltage relationship
Note: only ohmic and integrate_and_fire current voltage relationships are supported in current specification
Integrate and Fire
Voltage at which the mechanism causes the segment/cell to fire, i.e. membrane potential will be reset to v_reset
threshold = -50 mV
Refractory period
Time after a spike during which the segment will be clamped to v_reset (clamping current given by i = g_refrac*(v - v_reset))
t_refrac = 5 ms
Reset membrane potential
Membrane potential is reset to this after spiking
v_reset = -60 mV
Conductance dureing refractory period
Conductance during the period t_refrac after a spike, when the current due to this mechanism is given by i = g_refrac*(v - v_reset), therefore a high value for g_refrac, e.g. 100 microsiemens, will effectively clamp the cell at v_reset
g_refrac = 0.1 mS

Time to transform file: 0.137 secs